• Questions? Contact us! 308-334-5526

• We PRCD test all of our ADULTS

  PRA-prcd disease information

  Late form of Progressive Retinal Athrophy, called PRA-prcd (progressive rod-code degeneration), is just one of all retinal defects.

  Rods degenerate at first. Affected dogs become night-blind. This is very often the first symptom that dog owners recognize. Dogs usually have poor sense of directions and they crash in things. Pupil is widely open even when direct ray of light hit the eye (dogs have shining eyes in pictures). Later, cones start degenerating. Final disease symptoms are cataracts and total blindness.

  PRA-prcd defect arises after normal photoreceptors development. Degree of degeneration differs in parts of retina. Lower retina part is affected sooner and more than upper part (this is not obvious by ophthalmology examination). Disease recognition should be made during dog adolescence. Clinical diagnosis by electroretinogram (ERG) or opthalmoscopy of PRA-prcd can be difficult. ERG identifies affected animals sooner than opthalmoscopy.

  PRA-prcd is a hereditary disease. Causal mutation G1298A in ninth canine chromosome (CFA9)  PRA-prcd was recognized. This mutation is inherited as an autosomal recessive trait. That means the disease affects dogs with P/P genotype only.  The dogs with P/N genotype are considered carriers of the disease (heterozygotes). In offspring of two heterozygous animals following genotype distribution can be expected: 25 % N/N (healthy non-carriers), 25 % P/P (affected), and 50 % N/P (healthy carriers). Because of high risk of producing affected offspring, mating of two N/P animals (carriers) can not be recommended.

 

 

 

 

 

 

 

 

 

Questions, please Call Robin at  308-334-5526 or 308 340 0886

Delta and Harley due July

 

 

 

 

Harley and Deltas, they are sll PRCD negative, there is 1 red tri female she is PRCD negative.

 

 

 

 

 

Puppies range from $400 and up.

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